Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Amyloid beta A4 protein (Cell surface receptor)

Seq-ID:

P05067 [Homo sapiens]

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Interaction Network(s):

External Source(s):

MINT Interaction(s):

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GO-Terms:

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Molecular Function	Cellular Component	Biological Process
serine-type endopeptidase inhibitor activity, DNA binding, acetylcholine receptor binding, identical protein binding, metal ion binding, heparin binding	extracellular region, dendritic shaft, integral to plasma membrane, coated pit, cell surface, Golgi apparatus, platelet alpha granule lumen, axon, dendritic spine	dendrite development, G2 phase of mitotic cell cycle, positive regulation of mitotic cell cycle, regulation of multicellular organism growth, regulation of epidermal growth factor receptor activity, ionotropic glutamate receptor signaling pathway, mRNA polyadenylation, collateral sprouting in the absence of injury, adult locomotory behavior, extracellular matrix organization, Notch signaling pathway, regulation of translation, visual learning, neuron apoptosis, axon midline choice point recognition, cell adhesion, neuron remodeling, mating behavior, endocytosis, axon cargo transport, cellular copper ion homeostasis, protein amino acid phosphorylation, regulation of synapse structure and activity

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	743	HGVVEVDAAVTPEERHLSKMQ	GSK-3_beta	8764598	LTP	1.00	-	APP_amyloid	0.47	-	-
Y	757	RHLSKMQQNGYENPTYKFFEQ	-	11279131	LTP	1.00	ABL1 SH2; GRB2 SH2; SHC1 SH2	APP_amyloid	0.38	-	-
Y	757	RHLSKMQQNGYENPTYKFFEQ	-	18083107	HTP	1.00	ABL1 SH2; GRB2 SH2; SHC1 SH2	APP_amyloid	0.38	-	-
Y	762	MQQNGYENPTYKFFEQMQN	-	18083107	HTP	1.00	APBA1 PTB; APBA2 PTB; APBA3 PTB; APBB1 PTB; DAB1 PTB; MAPK8IP2 PTB	APP_amyloid	0.38	-	-

Amyloid beta A4 protein (Cell surface receptor)

Seq-ID:

P12023 [Mus musculus]

Download:

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
serine-type endopeptidase inhibitor activity, DNA binding, metal ion binding, heparin binding	cytoplasmic vesicle, neuromuscular junction, coated pit, integral to membrane, Golgi apparatus, apical part of cell, spindle midzone, axon, perinuclear region of cytoplasm, ciliary rootlet	dendrite development, smooth endoplasmic reticulum calcium ion homeostasis, G2 phase of mitotic cell cycle, positive regulation of mitotic cell cycle, regulation of multicellular organism growth, ionotropic glutamate receptor signaling pathway, mRNA polyadenylation, collateral sprouting in the absence of injury, adult locomotory behavior, extracellular matrix organization, Notch signaling pathway, regulation of translation, visual learning, synaptic growth at neuromuscular junction, axon midline choice point recognition, cell adhesion, neuron remodeling, neuromuscular process controlling balance, positive regulation of transcription from RNA polymerase II promoter, mating behavior, endocytosis, forebrain development, axon cargo transport, cellular copper ion homeostasis, protein amino acid phosphorylation, suckling behavior, regulation of synapse structure and activity, regulation of epidermal growth factor receptor activity

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	743	HGVVEVDAAVTPEERHLSKMQ	-	14722157	LTP	1.00		-	APP_amyloid	0.46	-	-
Y	757	RHLSKMQQNGYENPTYKFFEQ	-	11877420	LTP	1.00		-	APP_amyloid	0.38	-	-